The gene vdr encodes a transcriptional regulator that regulates the expression of supplement D-dependent genetics. The healthy proteins contains a zinc-finger DNA-binding domain, a transcriptional service domain and a ligand binding site. The necessary protein is a member of the steroid and thyroid body hormone receptor superfamily.
The T > C allele of the FokI polymorphism with the translation start off site of vdr results in a shortened oldetowntimes.net/how-do-air-bubbles-work protein that lacks a practical activation domain. It is characterized by decreased holding to transcribing factor IIB and reduced transactivation activity. The consistency of the variant allele varies among cultural groups. It is implicated in variations in calcium compression, bone vitamin density (BMD), and anthropometric measurements.
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